PD SENIOR SCIENTIST - DOWNSTREAM

Company: Cytovance Biologics
Location: Oklahoma City
Posted on: August 7, 2022

Job Description:

This website is AudioEye enabled and is being optimized for accessibility. To open the AudioEye Toolbar, press shift + =. The toolbar contains the followingThe AudioEye Help Desk to report accessibility and usability related issues.The AudioEye Certification Statement to explain the ongoing web accessibility and usability enhancements for this website.The Player tool to listen to this site read aloud. The Player is not intended as a substitute for your screen reader. If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process. PD SENIOR SCIENTIST - DOWNSTREAM Full Time Regular R&D Oklahoma City, OK, US 2 days ago Requisition ID: 1370 An Energetic Community - Headquartered in Downtown Oklahoma City, offering everything you look for in a modern metropolitan community. An abundance of arts, quality health care, excellence in education and more. It is a distinctly livable city where you can chase your dreams and still enjoy a rich quality of life. Visit abetterlifeokc.com A Competitive Benefit Package - Cytovance offers a competitive 401k match, medical benefits, Professional Development and Tuition Reimbursement, Paid Holidays, and a generous amount of paid time away from your job. HOW WILL YOU MAKE AN IMPACT? The Process Development Sr. Scientist leads multiple client projects to meet timeline, budget and scope commitments and has a good working knowledge of protein purification pertaining to the drug development process and knowledge of relevant business elements. The Senior Scientist keeps an up-to-date awareness of advances in multiple technological and scientific areas and has strong academic and industrial contacts. Supervision or mentoring other colleagues providing guidance, coaching and career development support is required. Essential Duties and Responsibilities: -

• Will be responsible for leading multiple client projects in parallel for protein purification.
• Work with R&D Directors and senior leadership on developing downstream purification processes for client projects along with innovative internal experiments.
• Serve as a point-of-contact and subject matter expert for chromatography method design, application and troubleshooting, buffer formulation, chromatography column packing, and TFF methods.
• Represent Cytovance and downstream technical area in client team meetings.
• Align client and business goals to enable both client and Cytovance success
• Supervise and perform downstream development
• Transfer downstream methods from R&D Services to the Cytovance MST group for transfer of process to manufacturing.
• Draft and review Standard Operating Procedures (SOP's)
• Draft and review Downstream Protocols, Batch Records, Slide Deck Data Summaries and Reports.
• Support other Downstream Scientists or Analysts by assisting in DSP troubleshooting measures and cross-review of results and notebooks
• Support additional R&D Services teams (cell-line development, upstream process development, and purification development) by generation, review, and/or interpretation of DSP results
• Support Manufacturing groups be leveraging protein purification expertise to support investigations and/or generation, review, and interpretation of purification results
• Operate, maintain, and qualify (I/O/PQ) laboratory equipment and software as required
• Specify, source, and assess new DSP technologies
• Perform data acquisition, reduction and evaluation
• Specify and source new downstream purification equipment to expand the purification capabilities of the downstream development laboratory
• Train others on purification techniques
• Mentor and teach others on purification theory and application
• Serve as a liaison with purification subcontractors
• Supervision of direct reports will be required
• Stay current with all training requirements. -
• Follow procedures reliably and consistently.
• Establish good working relationships with peers and other colleagues.
• Display a positive attitude and good flexibility.
• Proactively ensure good lab hygiene is being practiced.
• Apply technical and scientific knowledge to the overall direction of projects. Enable Cytovance to be using the most advance technology available. Acts as a scientific resource across disciplines.
• Make decisions that consistently require developing new options to solve complex problems.
• Use a high level of scientific judgment to adapt and/or create standard methods and techniques by applying breadth of knowledge and prior work experience.
• Work is performed under minimal supervision. Exercise considerable latitude in determining objectives of assignments.
• Identify and develop scientific strategies to support mid-term to long-term goals operational goals. -
• Represent technological areas and Cytovance's business perspectives at client project team meetings -
• Exemplify sound supervisory and training skills and take personal responsibility for the development of direct reports. - Job Requirements:
  • Ph.D., preferred in biochemistry or related science, with a combination of - ---4 -years of laboratory experience that may be a combination of Post -Doctoral, Academic or Industrial settings -
  • MS, in biochemistry or related science, with a minimum of 10 years directly related experience in protein purification -
  • Has extensive knowledge of protein purification procedures specifically for biopharmaceuticals
  • Has direct experience and training in chromatography method design, application and troubleshooting (affinity, ion exchange and HIC), TFF (flat cassette, hollow fiber), buffer formulation and chromatography column packing procedures.
  • Has broad knowledge of principles, concepts, and practices with a range of analytical techniques including ELISA, HPLC, enzymatic, and electrophoresis (SDS-PAGE, Western blots, IEF, & CE) procedures
  • Good working knowledge of scientific and technologic disciplines within pharmaceutical sciences
  • Good working knowledge of regulatory agencies and guidance documents governing GMP manufacturing such as ICH, FDA, and EMA.
  • Able to communicate technical details of projects and project strategy to clients and Cytovance client team members
  • Recommends and implements unique approaches to problem solving
  • Demonstrates good strategic project prioritization skills working in a multi-project environment
  • Critically evaluates information from a wide range of sources and makes clear recommendations
  • Able to work in a semi-independent manner and exercise good judgment based on experimental data -
  • Strong written and oral communication skills -
  • Able to read, analyze, and interpret common scientific and technical journals, financial reports, and legal documents.
  • Able to respond to common inquiries or complaints from customers, regulatory agencies, or members of the business community.
  • Able to write speeches and articles for publication that conform to prescribed style and format.
  • Able to effectively present information to top management, public groups, and/or boards of directors.
  • Able to define problems, collect data, establish facts, and draw valid conclusions. -
  • Able to interpret an extensive variety of technical instructions in mathematical or diagram form and deal with several abstract and concrete variables. Physical Demands: While performing the duties of this Job, the employee is regularly required to talk or hear. The employee is frequently required to stand and sit. The employee is occasionally required to walk; use hands to finger, handle, or feel; reach with hands and arms; climb or balance and stoop, kneel, crouch, or crawl. The employee must occasionally lift and/or move up to 25 pounds. While performing the duties of this Job, the employee is occasionally exposed to fumes or airborne particles and toxic or caustic chemicals consistent with a lab environment. The noise level in the work environment is usually moderate. Cytovance Biologics acknowledges that Providers may be a valuable resource for identifying and recruiting Candidates for employment. However, we require that all Recruiters engage directly with Cytovance Biologic's Human Resource Team and comply with Cytovance Biologic's requirements prior to transmitting any Resumes/CV's or introducing any Candidates to Cytovance Biologics. Cytovance Biologic's Human Resource Team is the only function within the Company that can enter contractual relationships with external Recruiters and Recruiting Agencies. We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class. -

Keywords: Cytovance Biologics, Oklahoma City , PD SENIOR SCIENTIST - DOWNSTREAM, Other , Oklahoma City, Oklahoma